Erythropoietin modulates bone marrow stromal cell differentiation
نویسندگان
چکیده
منابع مشابه
Bone marrow stromal cell blockade of human leukemic cell differentiation.
Bone marrow (BM) stromal cell inhibition of leukemic cell differentiation was studied in cellular coculture experiments. In coculture, a significant percentage of cells from the human myeloid leukemic cell lines HL-60, PLB-985, and K562 adhere to fibroblastic KM-102 BM stromal cells. A sensitive two-color immunofluorescence assay was developed to monitor stromal cellular effects upon leukemic c...
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Mechanical interaction of cells and their surroundings are prominent in mechanically active tissues such as cartilage. Chondrocytes regulate their growth, matrix synthesis, metabolism, and differentiation in response to mechanical loadings. Cells sense and respond to applied physical forces through mechanosensors such as integrin receptors. Herein, we examine the role of mechanical stimulation ...
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ژورنال
عنوان ژورنال: Bone Research
سال: 2019
ISSN: 2095-6231
DOI: 10.1038/s41413-019-0060-0